Euphoria-inducing substances - An Overview
The CB2R antagonist SR144528 reversed these effects, notably in C6 glioma cells, in which co-incubation triggered a 63% reduction in AJA’s inhibitory action on tumour expansion. This contrasted with THC, which was blocked by each CB1R and CB2R antagonists, further confirming that AJA’s antitumor efficacy is predominantly reliant on CB2 receptor